Both 尊 (ソン) and 敬 (ケイ) are read with their on'yomi. The long vowel for ケイ is important; そんけ is a common pronunciation error. It means to hold someone in high regard, showing admiration and reverence for their qualities or achievements.

尊敬は尊(ソン)と敬(ケイ)の音読みです。敬の長音を抜いた「そんけ」は誤りです。相手の優れた人格や能力などを認め、敬い、高く評価する気持ちを意味します。