「郵便局 (yūbinkyoku)」 means "post office." It's the place where you go to send letters and packages, buy stamps, or use other postal services. You often use 「へ (e)」 or 「に (ni)」 with it to show direction.
「郵便局(ゆうびんきょく)」は「手紙や荷物を送ったり、切手を買ったりする場所」という意味です。
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