バス ___ 会社へ 行きます。
The particle "で" (de) indicates the means or method by which an action is performed. When referring to transportation, it specifies the vehicle or mode used, such as going "by bus" in this sentence. It clarifies "how" you go.
助詞「で」は行為を行う手段や方法を示します。交通手段を言う時にも使われます。例：「タクシーで駅に行きます。」
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