絵画 (かいが) uses both characters with their On'yomi. 絵 (カイ) means 'picture' or 'drawing,' and 画 (ガ) also means 'picture' or 'painting.' While 絵 can be え, for this compound, かいが is correct. Readings like えかい or かいげ are incorrect. It is a general term for 'painting or picture' as a work of art.

絵画（かいが）は両方とも音読みです。絵（カイ）は「絵」、画（ガ）も「絵」を意味します。えかいや、かいげは誤り。紙やキャンバスに描かれた「絵画作品全般」を指します。