店 (みせ) means "shop" or "store." It refers to any place where you can buy things, from small convenience stores to larger department stores. You use it when talking about shopping or specific establishments. For example, 私はよくあの店に行きます。(Watashi wa yoku ano mise ni ikimasu.) means "I often go to that shop."

店(みせ)は「商品(しょうひん)を買(か)う場所(ばしょ)」という意味(いみ)です。買(か)い物(もの)に行(い)くときに使(つか)います。「この店(みせ)は有名(ゆうめい)です」のように使(つか)います。