to tackle; to work on; to engage in; to wrestle with
開発チームはシステムのパフォーマンス遅延問題を根本から解決するため、データベース構成の抜本的なリファクタリングに全員で_______ました。
In order to resolve the latency problem of the system from the root, all members of the development team tackled the drastic refactoring of the database configuration.
to handle, to manage, to undertake, to work on
彼は長年にわたり多くの大規模プロジェクトを手掛けてきた。
He has undertaken many large-scale projects over many years.
to handle, to undertake, to work on, to manage
彼は数々のヒット商品を手がけてきた。
He has worked on numerous hit products.